The spirit for Thrust Area 1 is collaborative intelligence, where humans and machines are joining forces to enable solutions to the NNSA’s problems of tomorrow. One of the pressing needs to address is a new era in additive manufacturing (AD) which has grown out a lab environment into a wide-spread use. While it is not an official field of its own, AD has gone through a number of breakthroughs to enable dramatic gains in speed, efficiency and cost. Specifically, in nuclear proliferation activities, AD may offer automated development of weapon complex components, technologies for micro-manufacturing and electronics-embedded circuitry. Moreover, automation, efficiency and scalability may enable fast and effective manufacturing of micro-reactors for potential production of special nuclear materials and energetic materials.